Publikationen (seit 2001)


  • Behrendt P, Feldheim M, Preusse-Prange A, Weitkamp JT, Haake M, Eglin D, Rolauffs B, Fay J, Seekamp A, Grodzinsky AJ, Kurz B. Chondrogenic potential of IL-10 in mechanically injured cartilage and cellularized collagen ACI grafts. Osteoarthritis Cartilage. 2018 Feb;26(2):264-275. doi: 10.1016/j.joca.2017.11.007. Epub 2017 Nov 21.
  • Rothdiener M, Uynuk-Ool T, Südkamp N, Aurich M, Grodzinsky AJ, Kurz B, Rolauffs B. Human osteoarthritic chondrons outnumber patient- and joint-matched chondrocytesin hydrogel culture-Future application in autologous cell-based OA cartilage repair? J Tissue Eng Regen Med. 2018 Feb;12(2):e1206-e1220. doi: 10.1002/term.2516. Epub 2017 Nov 8.


  • Behrendt P, Häfelein K, Preusse-Prange A, Bayer A, Seekamp A, Kurz B. IL-10 ameliorates TNF-α induced meniscus degeneration in mature meniscal tissue in vitro. BMC Musculoskelet Disord. 2017 May 16;18(1):197. doi: 10.1186/s12891-017-1561-x.
  • Uynuk-Ool T, Rothdiener M, Walters B, Hegemann M, Palm J, Nguyen P, Seeger T, Stöckle U, Stegemann JP, Aicher WK, Kurz B, Hart ML, Klein G, Rolauffs B. The geometrical shape of mesenchymal stromal cells measured by quantitative shape descriptors is determined by the stiffness of the biomaterial and by cyclic tensile forces. J Tissue Eng Regen Med. 2017 Dec;11(12):3508-3522. doi: 10.1002/term.2263. Epub 2017 Mar 29.
  • Häfelein K, Preuße-Prange A, Behrendt P, Kurz B. Selenium reduces early signs of Tumor necrosis factor alpha-induced meniscal tissue degradation. Biol Trace Elem Res. 2017 May;177(1):80-89. doi: 10.1007/s12011-016-0874-1. Epub 2016 Oct 25.


  • Rothdiener M, Hegemann M, Uynuk-Ool T, Walters B, Nguyen P, Claus V, Seeger T, Stoeckle U, Boehme KA,. Aicher WK, Stegemann JP, Hart ML, Kurz B, Klein G, Rolauffs B. Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition. Sci Rep. 2016 Oct 24;6:35840. doi: 10.1038/srep35840.
  • Behrendt P, Preusse-Prange A, Klüter T, Haake M, Rolauffs B, Grodzinsky AJ, Lippross S, Kurz B. IL-10 reduces apoptosis and extracellular matrix degradation after injurious compression of mature articular cartilage. Osteoarthritis Cartilage. 2016 Jun 24. pii: S1063-4584(16)30152-2. doi: 10.1016/j.joca.2016.06.016. [Epub ahead of print]
  • Felka T, Rothdiener M, Bast S, Uynuk-Ool T, Zouhair S, Ochs BG, De Zwart P, Stoeckle U, Aicher WK, Hart ML, Shiozawa T, Grodzinsky AJ, Schenke-Layland K, Venkatesan JK, Cucchiarini M, Madry H, Kurz B, Rolauffs B. Loss of spatial organization and destruction of the pericellular matrix in early  osteoarthritis in vivo and in a novel in vitro methodology. Osteoarthritis Cartilage. 2016 Jul;24(7):1200-9. doi: 10.1016/j.joca.2016.02.001. Epub 2016 Feb 12.
  • Bast BO, Winkler M, Kurz B. Reversed palmaris profundus muscle variation. International Journal of Anatomical Variations (2016) 9: 21–24


      • Mugunthan K, Doust J, Kurz B, Glasziou P. Is there sufficient evidence for tuning fork tests in diagnosing fractures? A systematic review. BMJ Open. 2014 Aug 4;4(8):e005238. doi: 10.1136/bmjopen-2014-005238.


              • Imgenberg J, Rolauffs B, Grodzinsky AJ, Schünke M, Kurz B (2013). Estrogen reduces mechanical injury-related cell death and proteoglycan degradation in mature articular cartilage independent of the presence of the superficial zone tissue. Osteoarthritis Cartilage. 2013 Nov;21(11):1738-45. doi: 10.1016/j.joca.2013.07.007. Epub 2013 Jul 14.
              • Florine EM, Miller RE, Porter RM, Evans CH, Kurz B, Grodzinsky AJ (2013). Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity: Comparison of Agarose and Self-Assembling Peptide Scaffolds. Cartilage. 2013 Jan 1;4(1):63-74.
              • Rolauffs B, Kurz B, Felka T, Rothdiener M, Uynuk-Ool T, Aurich M, Frank E, Bahrs C, Badke A, Stöckle U, Aicher WK, Grodzinsky AJ (2013). Stress-vs-time signals allow the prediction of structurally catastrophic events during fracturing of immature cartilage and predetermine the biomechanical, biochemical, and structural impairment. J Struct Biol. 2013 Sep;183(3):501-11. doi: 10.1016/j.jsb.2013.06.011. Epub 2013  Jun 28.
              • Hufeland M, Schünke M, Grodzinsky AJ, Imgenberg J, Kurz B (2013). Response of mature meniscal tissue to a single injurious compression and interleukin-1 in vitro.Osteoarthritis Cartilage. 2013 Jan;21(1):209-16. doi: 10.1016/j.joca.2012.10.003. Epub 2012 Oct 13.


                  • Steinhagen J, Niggemeyer O, Bruns J, Klebig F, Fuerst M, Ruether W, Schuenke M, Kurz B (2012). Modulation of bovine chondrocyte metabolism by free periosteal grafts in vitro. Int J Artif Organs. 2012 Feb;35(2):108-18. doi: 10.5301/ijao.5000081.


                      • Lippross S, Moeller B, Haas H, Tohidnezhad M, Steubesand N, Wruck CJ, Kurz B,  Seekamp A, Pufe T, Varoga D. Intraarticular injection of platelet-rich plasma reduces inflammation in a pig model of rheumatoid arthritis of the knee joint. Arthritis Rheum. 2011 Nov;63(11):3344-53. doi: 10.1002/art.30547.
                      • Rolauffs B, Rothdiener M, Bahrs C, Badke A, Weise K, Kuettner KE, Kurz B, Aurich M, Grodzinsky AJ, Aicher WK (2011). Onset of preclinical osteoarthritis: the angular spatial organization permits early diagnosis. Arthritis Rheum. 2011 Jun;63(6):1637-47. doi: 10.1002/art.30217.


                            • Rolauffs B, Muehleman C, Li J, Kurz B, Kuettner KE, Frank E, Grodzinsky AJ (2010). Vulnerability of the superficial zone of immature articular cartilage to compressive injury. Arthritis Rheum. 2010 Oct;62(10):3016-27. doi: 10.1002/art.27610.
                            • Birkenfeld F, Becker ME, Kurz B, Harder S, Kern M, Lucius R (2010). Changes in human mandibular bone morphology after heat application. Ann Anat. 2010 Aug 20;192(4):227-31. doi: 10.1016/j.aanat.2010.06.001. Epub 2010  Jun 12.
                            • Steinhagen J, Bruns J, Niggemeyer O, Fuerst M, Rüther W, Schünke M, Kurz B (2010). Perfusion culture system: Synovial fibroblasts modulate articular chondrocyte matrix synthesis in vitro. Tissue Cell. 2010 Jun;42(3):151-7. doi: 10.1016/j.tice.2010.03.003. Epub 2010 Apr 28.
                            • Gille J, Kunow J, Boisch L, Behrens P, Bos I, Hoffmann C, Köller W, Russlies M, and Kurz B (2010). Cell-Laden and Cell-Free Matrix-Induced Chondrogenesis versus Microfracture for the Treatment of Articular Cartilage Defects: A Histological and Biomechanical Study in Sheep.
                              Cartilage, January 7, [Epub ahead of print]; doi:10.1177/1947603509358721
                            • Krenn V, Knöß P, Rüther W, Jakobs M, Otto M, Krukemeyer MG, Heine A, Möllenhoff G, Kurz B (2010). Meniscal degeneration score and NITEGE expression : Immunohistochemical detection of NITEGE in advanced meniscal degeneration.
                              Orthopade. 2010 39(5):475-85
                            • Lemke AK, Sandy JD, Voigt H, Dreier R, Lee JH, Grodzinsky AJ, Mentlein R, Fay J, Schünke M, Kurz B (2010). Interleukin-1alpha treatment of meniscal explants stimulates the production and release of aggrecanase-generated, GAG-substituted aggrecan products and also the release of pre-formed, aggrecanase-generated G1 and m-calpain-generated G1-G2.
                              Cell Tissue Res. 340(1):179-88
                            • Krenn V, Kurz B, Krukemeyer MG, Knoess P, Jakobs M, Poremba C, Möllenhoff G (2010).
                              Histopathological degeneration score of fibrous cartilage : Low- and high-grade meniscal degeneration. Z Rheumatol. 69(7):644-52.
                            • Warnke PH, Russo PAJ, Hopfenziz M, Kurz B, Becker ST, Sherry E, Springer I, and Sivananthan S (2010) Rhinoplasty and Otoplasty: Antimicrobial Peptide Immunity Protects Human Nasal and Auricular Cartilage Against Infection. J Craniofac Surg. Jan;21(1):198-201.
                            • Akay I, Oxmann D, Helfenstein A, Mentlein R, Schünke M, Hassenpflug J, Kurz B (2010)
                              Tumor risk by Tissue Engineering: Cartilaginous Differentiation of Mesenchymal Stem Cells reduces Tumor Growth. Osteoarthritis Cartilage. Mar;18(3):389-96. Epub 2009 Dec 4.
                            • Schaefer PJ, Kurz B, Schaefer FK, Hedderich J, Strutz A, Heller, Jahnke T (2010)
                              Development of a Permanently Controllable Rotating Biopsy Device, Part II: Competitive In-Vitro Testing of a Cannula-like Prototype Compared to Established End-Cut and Side-Notch Biopsy Devices. Rofo. Jan;182(1):58-65. Epub 2009 Oct 26.
                            • Kopesky PW, Vanderploeg EJ, Sandy J, Kurz B, Grodzinsky A (2010)
                              Self-Assembling Peptide Hydrogels Modulate In Vitro Chondrogenesis of Bovine Bone Marrow Stromal Cells. Tissue Eng Part A. 2010 Feb;16(2):465-77


                                • Krebs A, Graeff C, Frieling I, Kurz B, Timm W, Engelke K, Glüer CC (2009)
                                  High resolution computed tomography of the vertebrae yields accurate information on trabecular distances if processed by 3D fuzzy segmentation approaches.
                                  Bone 44(1):145-52.
                                • Patwari P, Lin SN, Kurz B, Cole AA, Kumar S, Grodzinsky AJ (2009)
                                  Potent inhibition of cartilage biosynthesis by coincubation with joint capsule through an IL-1-independent pathway.
                                  Scand J Med Sci Sports ;19(4):528-35. Epub 2009 Apr 2.
                                • Voigt H, Lemke AK, Mentlein R, Schunke M, Kurz B (2009)
                                  Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitric oxide-independent aggrecanase activity in vitro.
                                  Arthritis Res Ther. 2009 Sep 24;11(5):R141. [Epub ahead of print]


                                  • Claassen H, Briese V, Manapov F, Nebe B, Schünke M, Kurz B (2008) The phytoestrogens daidzein and genistein enhance the insulin-stimulated sulfate uptake in articular chondrocytes. Cell Tissue Res 333(1):71-9.


                                    • Henrotin Y, Kurz B (2007) Antioxidant to treat osteoarthritis : dream or reality?
                                      Curr Drug Target, 8(2):347-57.
                                    • Henrotin Y, Blanco FJ, Aigner T, Kurz B (2007) The Significance of Oxidative Stress in Articular Cartilage Ageing and Degradation. Curr Rheumatol Rev, 3(4):261-274
                                    • Maurer J, Fuchs S, Jager R, Kurz B, Sommer L, Schorle H (2007)
                                      Establishment and controlled differentiation of neural crest stem cell lines using conditional transgenesis. Differentiation. 75(7):580-91
                                    • Schaefer FK, Kurz B, Schaefer PJ, Fuerst M, Hedderich J, Graessner J, Schuenke M, Heller H. (2007) Accuracy and precision in the detection of articular cartilage lesions using magnetic resonance imaging at 1.5 Tesla in an in vitro study with orthopedic and histopathologic correlation. Acta Radiol. 48(10):1131-7.


                                        • Fay J, Varoga D, Wruck CJ, Kurz B, Goldring MB, Pufe T (2006)
                                          Reactive oxygen species induce expression of vascular endothelial growth
                                          factor in chondrocytes and human articular cartilage explants.
                                          Arthritis Res Ther 28(6):R189.
                                        • Claassen H, Cellarius C, Scholz-Ahrens KE, Schrezenmeir J, Gluer CC,
                                          Schünke M, Kurz B (2006) Extracellular matrix changes in knee joint cartilage following
                                          bone-active drug treatment. Cell Tissue Res 324(2):279-89
                                        • Behrens P, Bitter T, Kurz B, Russlies M (2006)
                                          Matrix-associated autologous chondrocyte transplantation/implantation (MACT/MACI)-5-year follow-up. Knee 13(3):194-202
                                        • Claassen H, Schluter M, Schunke M, Kurz B (2006)
                                          Influence of 17beta-estradiol and insulin on type II collagen and protein
                                          synthesis of articular chondrocytes. Bone 39(2):310-7
                                        • Varoga D, Paulsen F, Mentlein R, Fay J, Kurz B, Schutz R, Wruck C, Goldring M, Pufe T (2006)
                                          TLR-2-mediated induction of vascular endothelial growth factor (VEGF) in cartilage in septic joint disease. J Pathol. 2006 Sep 18; [Epub ahead of print]


                                            • Russlies M, Behrens P, Ehlers EM, Bröhl C, Vindigni C, Spector M, Kurz B. (2005)
                                              Periosteum stimulates subchondral bone densification in autologous chondrocyte transplantation in a sheep model. Cell Tiss Res 319(1):133-42
                                            • Kisiday JD, Kurz B, DiMicco MA, Grodzinsky AJ (2005)
                                              Evaluation of medium supplemented with insulin-transferrin-selenium for culture of primary bovine calf chondrocytes in three-dimensional hydrogel scaffolds. Tissue Eng. 11(1-2):141-151
                                            • Claassen H, Schünke M, Kurz B (2005)
                                              Estradiol protects cultured articular chondrocytes from oxygen-radical-induced damage. Cell Tissue Res 319(3):439-45
                                            • Henrotin Y, Kurz B, Aigner T (2005)
                                              Oxygen and reactive oxygen species in articular cartilage degradation: friends or foes? Osteoarthritis Cartilage, 13(8):643-54
                                            • Kurz B, Lemke AK, Fay J, Pufe T, Grodzinsky AJ, Schünke M. (2005)
                                              Pathomechanisms of cartilage destruction by mechanical injury. Ann Anat, 187(5-6):473-85
                                            • Pufe T, Kurz B, Petersen W, Varoga D, Mentlein R, Lemke A, Tillmann B (2005)
                                              The influence of biomechanical parameters on the expression of VEGF and endostatin in the bone and joint system. Ann Anat, 187(5-6):461-72


                                                • Scherer K, Schünke M, Sellckau R, Hassenpflug J, Kurz B (2004)
                                                  The influence of oxygen and hydrostatic pressure on articular chondrocytes and adherent bone marrow cells in vitro.
                                                  Biorheology 41(3-4):323-33
                                                • Kurz B, Lemke A, Kehn M, Domm C, Patwari P, Frank E, Grodzinsky AJ, Schünke M (2004)
                                                  Tissue maturation and antioxidants alter the apoptotic response of articular cartilage after injurious compression.
                                                  Arthritis Rheum 50(1): 123-130
                                                • Pufe T, Lemke A, Kurz B, Petersen W, Tillmann B, Grodzinsky AJ, Mentlein R (2004)
                                                  Mechanical overload induces VEGF in cartilage discs via hypoxia-inducible factor.
                                                  Am J Pathol 164(1): 185-92
                                                • Kisiday JD, Jin M, DiMicco MA, Kurz B, Grodzinsky AJ (2004) Effects of Dynamic Compressive Loading on Chondrocyte Biosynthesis in Self-Assembling Peptide Scaffolds,
                                                  J Biomech 37:595-604
                                                • Kurz B, Domm C, Jin M, Sellckau R, Schünke M (2004)  Tissue engineering of articular cartilage under the influence of collagen I/III-membranes and low oxygen tension.
                                                  Tissue Eng 10:1277-86
                                                • Domm C, Schünke M, Steinhagen J, Freitag S, Kurz B (2004)
                                                  Influence of various alginate brands on the redifferentiation of dedifferentiated bovine articular chondrocytes in alginate bead culture under high and low oxygen tension.
                                                  Tissue Eng 10(11-12):1796-1805


                                                    • Ailland J, Kampen WU, Schünke M, Trentmann J, Kurz B (2003) Beta-irradiation decreases collagen type II-synthesis and increases NO-production and cell death in articular chondrocytes. Ann Rheum Dis 62(11): 1054-60.
                                                    • Pufe T, Petersen W, Kurz B, Tsokos M, Tillmann B, Mentlein R Petersen W (2003) Mechanical factors influence the expression of endostatin - an inhibitor of angiogenesis - in tendons. J Orthop Res 21:610-6
                                                    • Kurz B, Schünke M (2003) Physiko-mechanische Stimulation von Zellen am Beispiel des Gelenkknorpels. In "Tissue Engineering: Neues zum Gewebeersatz im Muskel-Skelett-System", Ed. Bruns J, Steinkopff Verlag, S. 11-20


                                                        • Domm C, Schünke M, Christesen K and Kurz B (2002) Redifferentiation of dedifferentiated bovine articular chondrocytes in alginate culture under low oxygen tension. Osteoarthritis Cartilage 10:13-22
                                                        • Kurz B, Jost B and Schünke M (2002) Dietary vitamins and selenium diminish the development of mechanically  induced osteoarthritis and increase the expression of antioxidative enzymes in the knee joint of STR/1N mice.  Osteoarthritis Cartilage 10:119-126
                                                        • Claassen H, Hornberger F, Scholz-Ahrens K, Schunke M, Schrezenmeir J, Kurz B (2002) The effect of estrogens and  dietary calcium deficiency on the extracellular matrix of articular cartilage in Gottingen miniature pigs. Ann Anat  184:141-148
                                                        • Petersen W, Pufe T, Kurz B, Mentlein R, Tillmann B (2002) Angiogenesis in fetal tendon development: Spatial and  temporal expression of the angiogenic peptide vascular endothelial growth factor (VEGF). Anat & Embryol 205:263-270
                                                        • Kisiday J, Jin M, Kurz B, Hung H, Semino C, Zhang S, Grodzinsky AJ (2002) Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair.  Proc Nat Acad Sci 99:9996-10001
                                                        • Aigner T, Kurz B, Fukui N, Sandell L (2002) Roles of chondrocytes in the pathogenesis of osteoarthritis. Curr Opin  Rheumatol 14:578-84


                                                            • Claassen H, Hassenpflug J, Schünke M, Sierralta W, Thole H and Kurz B (2001) Immunohistochemical detection of  estrogen receptor alpha in articular chondrocytes from cows, pigs, and humans: in situ and in vitro results.
                                                              Ann Anat 183:1-5
                                                            • Hansen U, Schünke M, Domm C, Ioannidis N, Hassenpflug J, Gehrke T and Kurz B (2001) Combination of reduced oxygen tension and intermittent hydrostatic pressure: a useful tool in articular cartilage tissue engineering. J Biomech 34:941-949
                                                            • Kurz B, Jin M, Patwari P, Cheng DM, Lark MW and Grodzinsky AJ (2001) Biosynthetic response and mechanical  properties of articular cartilage after injurious compression. J Orthop Res 19:1140-1146 
                                                            • Steinhagen J, Kurz B, Niggemeyer O, Bruns J (2001) The pathophysiology of cartilage diseases. Ortopedia Traumatologia Rehabilitacja 3(2):163-168